51. Which of the following is not true of sulfonamides ?
(a) They are primarily metabolized by acetylation
(b) They are more likely to produce crystalluria in alkaline urine in which they are less soluble
(c) They may exert bactericidal action in the urinary tract
(d) Used alone, they have become therapeutically unreliable for serious infections
Ans: B
52. Adverse effects of ciprofloxacin are referable primarily to the following except
(a) Gastrointestinal tract
(b) Kidney
(c) Skin
(d) Nervous system
Ans: B
53. A single oral dose of the following drug can cure most cases of uncomplicated gonorrhoea
(a) Ciprofloxacin
(b) Cotrimoxazole
(c) Spectinomycin
(d) Doxycycline
Ans: A
54. Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ?
(a) Pefloxacin
(b) Ciprofloxacin
(c) Sparfloxacin
(d) Norfloxacin
Ans: C
55. A woman has an upper respiratory infection.
Six years ago, she experienced an episode of bronchospasm follwing penicillin V therapy. The cultures now reveal a strain of streptococcus pneumoniae
that is sensitive to all of the following drugs. Which of these drugs would be the best choice for this patient?
(a) Amoxicillin/clavulanate
(b) Erythromycin
(c) Ampicillin
(d) cefaclor
(e) Cyclacillin
Ans: B
56. Important microbiological features of ciprofloxacin include the following except
(a) Long postantibiotic effect
(b) Marked suppression of intestinal anaerobes
(c) MBC values close to MIC values
(d) Slow development of resistance
Ans: B
57. Currently the drug of choice for emperic treatment of typhoid fever is
(a) Chloramphenicol
(b) Cotrimoxaxole
(c) Ciprofloxacin
(d) Ampicillin
Ans: C
58. In the treatment of typhoid fever, ciprofloxacin has the following advantage(s)
(a) It is effective in nearly all cases
(b) Early abetment of fever and other symptoms
(c) Development of carrier state is less likely
(d) All of the above
Ans: D
59. Penicillins interfere with bacterial cell wall synthesis by
(a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide
(b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl glucosamine
(c) Inhibiting transpeptidases and carboxy
peptidases which cross link the peptidoglycan residues
(d) Counterfeiting for D-alanine in the bacterial cell wall
Ans: C
60. All of the following drugs are suitable oral therapy for a lower urinary tract infection due to Pseudomonas aeruginosa except
(a) Norfloxacin
(b) Trimethoprim-sulfamethxazole
(c) Ciprofloxacin
(d) Carbenicillin
(e) Methenamine mandelate
Ans: B
(a) They are primarily metabolized by acetylation
(b) They are more likely to produce crystalluria in alkaline urine in which they are less soluble
(c) They may exert bactericidal action in the urinary tract
(d) Used alone, they have become therapeutically unreliable for serious infections
Ans: B
52. Adverse effects of ciprofloxacin are referable primarily to the following except
(a) Gastrointestinal tract
(b) Kidney
(c) Skin
(d) Nervous system
Ans: B
53. A single oral dose of the following drug can cure most cases of uncomplicated gonorrhoea
(a) Ciprofloxacin
(b) Cotrimoxazole
(c) Spectinomycin
(d) Doxycycline
Ans: A
54. Which fluoroquinolone has markedly enhanced activity against gram positive bacteria and anaerobes ?
(a) Pefloxacin
(b) Ciprofloxacin
(c) Sparfloxacin
(d) Norfloxacin
Ans: C
55. A woman has an upper respiratory infection.
Six years ago, she experienced an episode of bronchospasm follwing penicillin V therapy. The cultures now reveal a strain of streptococcus pneumoniae
that is sensitive to all of the following drugs. Which of these drugs would be the best choice for this patient?
(a) Amoxicillin/clavulanate
(b) Erythromycin
(c) Ampicillin
(d) cefaclor
(e) Cyclacillin
Ans: B
56. Important microbiological features of ciprofloxacin include the following except
(a) Long postantibiotic effect
(b) Marked suppression of intestinal anaerobes
(c) MBC values close to MIC values
(d) Slow development of resistance
Ans: B
57. Currently the drug of choice for emperic treatment of typhoid fever is
(a) Chloramphenicol
(b) Cotrimoxaxole
(c) Ciprofloxacin
(d) Ampicillin
Ans: C
58. In the treatment of typhoid fever, ciprofloxacin has the following advantage(s)
(a) It is effective in nearly all cases
(b) Early abetment of fever and other symptoms
(c) Development of carrier state is less likely
(d) All of the above
Ans: D
59. Penicillins interfere with bacterial cell wall synthesis by
(a) Inhibiting synthesis of N-acetyl muramic acid pentapeptide
(b) Inhibiting conjugation between N-acetyl muramic acid and N-acetyl glucosamine
(c) Inhibiting transpeptidases and carboxy
peptidases which cross link the peptidoglycan residues
(d) Counterfeiting for D-alanine in the bacterial cell wall
Ans: C
60. All of the following drugs are suitable oral therapy for a lower urinary tract infection due to Pseudomonas aeruginosa except
(a) Norfloxacin
(b) Trimethoprim-sulfamethxazole
(c) Ciprofloxacin
(d) Carbenicillin
(e) Methenamine mandelate
Ans: B
I was cured of HPV with the use of pure natural roots and herbs from a herbal professional maker called dr Moses Buba, a man of trust and always reliable to his word. I actually thank you cause at first I doubt what others do, but you make me believe that good people still live . You can reach via email buba.herbalmiraclemedicine@gmail.com or WhatsApp him +234906059305 for more information you can reach me also on my cell phone with text or WhatsApp and even drop a call on 0(501)9914802 . am grateful to share his work so I will share more about Dr Moses buba
ReplyDeleteI was cured of HPV with the use of pure natural roots and herbs from a herbal professional maker called dr Moses Buba, a man of trust and always reliable to his word. I actually thank you cause at first I doubt what others do, but you make me believe that good people still live . You can reach via email buba.herbalmiraclemedicine@gmail.com or WhatsApp him +234906059305 for more information you can reach me also on my cell phone with text or WhatsApp and even drop a call on 0(501)9914802 . am grateful to share his work so I will share more about Dr Moses buba