Wednesday 28 October 2015

Frequently Asked AntiBiotics Objective Type Questions And Answers

71. Clavulanic acid is combined with amoxicillin because
(a) It kills bacteria that are not killed by-moxicillin
(b) It reduces renal clearance of amoxicillin
(c) It counteracts the adverse effects of amoxicillin
(d) It inhibits beta lactamases that destroy amoxicillin
Ans: D

72. Amoxicillin + Clavulanic acid is active against the following organism except
(a) Methicillin resistant Staph. aureus
(b) Penicillinase producing Staph. aureus
(c) Penicillinase producing n. gonorrhoeae
(d) ß-lactamase producing E. coli
Ans: A

73. A woman’s neglected hangnail has developed into a mild staphylococcal cellulites. Which of the following regimens would be appropriate oral therapy?
(a) Dicloxacillin 125 mg q6h
(b) Vancomycin 250 mg q6h
(c) Methicillin 500 mg q6h
(d) Cefazolin 1 g q8h
(e) Penicillin V 500 mg q6h
Ans: A

74. Cefotaxime has the following properties except
(a) It is highly active against aerobic gram negative bacteria
(b) It is the most active cephalosporin against Pseudomonas aeruginosa
(c) It produces an active metabolite
(d) It has achieved high cure rates in serious hospital acquired infections
Ans: B

75. Select the fourth generation cephalosporin among the following
(a) Cefpirome
(b) Ceftizoxime
(c) Ceftazidime
(d) Cefuroxime
Ans: A

76. The most important mechanism by which tetracycline antibiotics exert antiimicrobial action is
(a) They chelate Ca2+ ions and alter permeability of bacterial cell membrane
(b) They bind to 30S ribosomes and inhibit bacterial protein synthesis
(c) They bind to 50S ribosomes and interfere with translocation of the growing peptide chain in the bacteria
(d) They interfere with DNA mediated RNA synthesis in bacteria
Ans: B

77. Select the most potent tetracycline antibiotic
(a) Demeclocycline
(b) Methacycline
(c) Minocycline
(d) Doxycycline
Ans: C

78. An 8-year-old child presented with brownish discoloured and deformed anterior teeth. History of having received an antibiotic about 4 years earlier was
obtained. Which antibiotic could be responsible for the condition ?
(a) Chloramphenicol
(b) Tetracycline
(c) Erythromycin
(d) Genetamicin
Ans: B

79. The most suitable tetracycline for use in a patient with impaired renal function is
(a) Chlortetracycline
(b) Demeclocycline
(c) oxytetracycine
(d) Doxycycline
Ans: D

80. Compared to older tetracyclines, doxycycline produces a lower incidence of superinfection diarrhoea because
(a) It is completely absorbed in the small intestines so that drug concentration in the colonic contents is low
(b) It is inactivated by the gut microflora
(c) It is not active against the microbes of the normal gut flora
(d) It is a potent tetracycline and inhibits the superinfection causing microbes as well
Ans: A

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1 comment:

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    I was cured of HPV  with the use of pure natural roots and herbs from a herbal professional maker called dr Moses Buba, a man of trust and always reliable to his word. I actually thank you cause at first I doubt what others do, but you make me believe that good people still live . You can reach via email buba.herbalmiraclemedicine@gmail.com or WhatsApp him  +234906059305 for more information you can reach me also on my cell phone with text or WhatsApp and even drop a call on 0(501)9914802 . am grateful to share his work so I will share more about Dr Moses buba 

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