81. Tetracyclines are still the first choice drugs for the following disease.
(a) Granuloma linguinale
(b) Chancroid
(c) Syphilis
(d) Gonorrhoea in patients allergic to penicillin
Ans: A
82. Chloramphenicol is more active than tetracyclines against
(a) Bateroides fragilis
(b) Treponema pallidum
(c) Streptococci
(d) Staphylococci
Ans: A
83. Which out of the following antibiotics penetrates blood-CSF barrier the best
(a) Erythromycin
(b) Gentamicin
(c) Tetracycline
(d) Chloramphenicol
Ans: D
84. The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is
(a) Decreased permeability into the bacterial cell
(b) Acquisition of a plasmid encoded for chloramphenicol acetyl transferase
(c) Lowered affinity of the bacterial ribosome for chloramphenicol
(d) Switching over from ribosomal to mitochondrial protein synthesis
Ans: B
85. What is the most important reason for restricted clinical use of chloramphenicol ?
(a) Its narrow spectrum of activity
(b) Emergence of chloramphenicol resistance
(c) Its potential to cause bone marrow depression
(d) Its potential to cause superinfections
Ans: C
86. Aminoglycoside antibiotics have the following common property
(a) They are primarily active against gramnegative bacilli
(b) They are more active in acidic medium
(c) They readily enter cells and are distributed in total body water
(d) They are nearly completely metabolized in liver
Ans: A
87. Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ?
(a) Streptomycin
(b) Gentamicin
(c) Kanamycin
(d) Sisomicin
Ans: C
88. Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)?
(a) Vancomycin
(b) Clarithromycin
(c) Erythromycin base
(d) Troleandomycin
(e) Erythromycin estolate
Ans: B
89. The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is
(a) Plasmid mediated acquisition of aminoglycoside conjugating enzyme
(b) Mutational acquisition of aminoglycoside hydrolyzing enzyme
(c) Mutation reducing affinity of ribosomal protein for the antibiotic
(d) Mutational loss of porin channels
Ans: A
90. Which toxic effect of aminoglycoside antibiotics is most irreversible in nature ?
(a) Vestibular damage
(b) Hearing loss
(c) Neuromuscular blockade
(d) Kidney damage
Ans: B
(a) Granuloma linguinale
(b) Chancroid
(c) Syphilis
(d) Gonorrhoea in patients allergic to penicillin
Ans: A
82. Chloramphenicol is more active than tetracyclines against
(a) Bateroides fragilis
(b) Treponema pallidum
(c) Streptococci
(d) Staphylococci
Ans: A
83. Which out of the following antibiotics penetrates blood-CSF barrier the best
(a) Erythromycin
(b) Gentamicin
(c) Tetracycline
(d) Chloramphenicol
Ans: D
84. The most important mechanism by which gram negative bacilli acquire chloramphenicol resistance is
(a) Decreased permeability into the bacterial cell
(b) Acquisition of a plasmid encoded for chloramphenicol acetyl transferase
(c) Lowered affinity of the bacterial ribosome for chloramphenicol
(d) Switching over from ribosomal to mitochondrial protein synthesis
Ans: B
85. What is the most important reason for restricted clinical use of chloramphenicol ?
(a) Its narrow spectrum of activity
(b) Emergence of chloramphenicol resistance
(c) Its potential to cause bone marrow depression
(d) Its potential to cause superinfections
Ans: C
86. Aminoglycoside antibiotics have the following common property
(a) They are primarily active against gramnegative bacilli
(b) They are more active in acidic medium
(c) They readily enter cells and are distributed in total body water
(d) They are nearly completely metabolized in liver
Ans: A
87. Which aminoglycoside antibiotic causes more hearing loss than vestibular disturabance as toxic effect ?
(a) Streptomycin
(b) Gentamicin
(c) Kanamycin
(d) Sisomicin
Ans: C
88. Which of the following drugs has demonstrated in vitro activity against Mycobacterium avium-intracellular(MAI)?
(a) Vancomycin
(b) Clarithromycin
(c) Erythromycin base
(d) Troleandomycin
(e) Erythromycin estolate
Ans: B
89. The most important mechanism of bacterial resistance to an aminoglycoside antibiotic is
(a) Plasmid mediated acquisition of aminoglycoside conjugating enzyme
(b) Mutational acquisition of aminoglycoside hydrolyzing enzyme
(c) Mutation reducing affinity of ribosomal protein for the antibiotic
(d) Mutational loss of porin channels
Ans: A
90. Which toxic effect of aminoglycoside antibiotics is most irreversible in nature ?
(a) Vestibular damage
(b) Hearing loss
(c) Neuromuscular blockade
(d) Kidney damage
Ans: B
More Questions & Answers:-
I was cured of HPV with the use of pure natural roots and herbs from a herbal professional maker called dr Moses Buba, a man of trust and always reliable to his word. I actually thank you cause at first I doubt what others do, but you make me believe that good people still live . You can reach via email buba.herbalmiraclemedicine@gmail.com or WhatsApp him +234906059305 for more information you can reach me also on my cell phone with text or WhatsApp and even drop a call on 0(501)9914802 . am grateful to share his work so I will share more about Dr Moses buba
ReplyDeleteI was cured of HPV with the use of pure natural roots and herbs from a herbal professional maker called dr Moses Buba, a man of trust and always reliable to his word. I actually thank you cause at first I doubt what others do, but you make me believe that good people still live . You can reach via email buba.herbalmiraclemedicine@gmail.com or WhatsApp him +234906059305 for more information you can reach me also on my cell phone with text or WhatsApp and even drop a call on 0(501)9914802 . am grateful to share his work so I will share more about Dr Moses buba