41. Which of the following has been shown to prolong life in patient with chronic congestive failure but has a negative inotropic effect on cardiac contractility?
(a) Carvedilol
(b) Digitoxin
(c) Digoxin
(d) Dobutamine
(e) Enalapril
Ans: A
42. Which of the following is the drug of choice in treating suicidal overdose of digitoxin ?
(a) Digoxin antibodies
(b) Lidocaine
(c) Magnesium
(d) Potassium
(e) Quinidine
Ans: A
43. When used as an antiarrhythmic drug, Lidocaine typically
(a) Increases action potential duration
(b) Increases contractility
(c) Increses PR interval
(d) Reduces abnormal automaticity
(e) Reduces resting potential
Ans: D
44. A 16-year-old-girl is found to have paroxysmal attacks of rapid heart rate. The antiarrhythmic of choice in most cases of acute AV nodal tachycardia is
(a) Adenosine
(b) Amiodarone
(c) Flecainide
(d) Propranolol
(e) Quinidine
Ans: A
45. Recognized adverse effects of quinidine include which one of the following?
(a) Cinchonism
(b) Constipation
(c) Lupus erythematosus
(d) Increase in digoxin clearance
(e) Precipitation of hyperthyroidism
Ans: A
46. Following is an antagonist of ganglion type nicotinic receptors
(a) Tubercurarine
(b) a-bungarotoxin
(c) Trimethaphan
(d) All of the above
Ans: C
47. Which of the following is an orally active drug that blocks sodium channels and decreases action potential duration?
(a) Adenosine
(b) Amiodarone
(c) Disopyramide
(d) Esmolol
(e) Mexiletine
Ans: E
48. Which of the following has the longest half-life of all antiarrhythmic drugs?
(a) Adenosine
(b) Amiodarone
(c) Disopyramide
(d) Esmolol
(e) Flecainide
Ans: B
49. Which of the following diuretics would be most useful in a patient with cerebral edema?
(a) Acetazolamide
(b) Amiloride
(c) Ethacrynic acid
(d) Furosemide
(e) Mannitol
Ans: E
50. Which of the following therapies would be most useful in the management of severe hypercalcemia?
(a) Amiloride plus saline infusion
(b) Furosemide plus saline infusion
(c) Hydrochlorothiazide plus saline infusion
(d) Mannitol plus saline infusion
(e) Spironolactone plus saline infusion
Ans: B
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(a) Carvedilol
(b) Digitoxin
(c) Digoxin
(d) Dobutamine
(e) Enalapril
Ans: A
42. Which of the following is the drug of choice in treating suicidal overdose of digitoxin ?
(a) Digoxin antibodies
(b) Lidocaine
(c) Magnesium
(d) Potassium
(e) Quinidine
Ans: A
43. When used as an antiarrhythmic drug, Lidocaine typically
(a) Increases action potential duration
(b) Increases contractility
(c) Increses PR interval
(d) Reduces abnormal automaticity
(e) Reduces resting potential
Ans: D
44. A 16-year-old-girl is found to have paroxysmal attacks of rapid heart rate. The antiarrhythmic of choice in most cases of acute AV nodal tachycardia is
(a) Adenosine
(b) Amiodarone
(c) Flecainide
(d) Propranolol
(e) Quinidine
Ans: A
45. Recognized adverse effects of quinidine include which one of the following?
(a) Cinchonism
(b) Constipation
(c) Lupus erythematosus
(d) Increase in digoxin clearance
(e) Precipitation of hyperthyroidism
Ans: A
46. Following is an antagonist of ganglion type nicotinic receptors
(a) Tubercurarine
(b) a-bungarotoxin
(c) Trimethaphan
(d) All of the above
Ans: C
47. Which of the following is an orally active drug that blocks sodium channels and decreases action potential duration?
(a) Adenosine
(b) Amiodarone
(c) Disopyramide
(d) Esmolol
(e) Mexiletine
Ans: E
48. Which of the following has the longest half-life of all antiarrhythmic drugs?
(a) Adenosine
(b) Amiodarone
(c) Disopyramide
(d) Esmolol
(e) Flecainide
Ans: B
49. Which of the following diuretics would be most useful in a patient with cerebral edema?
(a) Acetazolamide
(b) Amiloride
(c) Ethacrynic acid
(d) Furosemide
(e) Mannitol
Ans: E
50. Which of the following therapies would be most useful in the management of severe hypercalcemia?
(a) Amiloride plus saline infusion
(b) Furosemide plus saline infusion
(c) Hydrochlorothiazide plus saline infusion
(d) Mannitol plus saline infusion
(e) Spironolactone plus saline infusion
Ans: B
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