Thursday 29 October 2015

Common Drugs Acting On Autonomous Nervous System Objective Type Questions And Answers

31. Denervation super-sensitivity includes
(a) Proliferation of receptors
(b) Loss of mechanism for transmitter removal
(c) Increased post-junctional responsiveness
(d) All of the above
Ans: D

32. Which of the following is approved for the treatment of hemorrhagic stroke ?
(a) Amyl nitrite
(b) Hydralazine
(c) Isosorbide moninitrate
(d) Nifedipine
(e) Nimodipine
Ans: E

33. Which of the following drugs used for the treatment of angina by inhalation has a very rapid onset and a brief duration of effect ?
(a) Amyl nitrite
(b) Hydralazine
(c) Isosorbide mononitrate
(d) Nifedipine
(e) Nimodipine
Ans: A

34. Which of the following is a vasodilator drug used for hypertension that lacks a direct effect on autonomic receptors but may provoke anginal attacks?
(a) Amyl nitrite
(b) Hydralazine
(c) Isosorbide mononitrate
(d) Nifedipine
(e) Nimodipine
Ans: B

35. The biochemical mechanism of action of digitalis is associated with
(a) A decrease in calcium uptake by the sarcoplasmic reticulum
(b) An increase in ATP synthesis
(c) A modification of the actin molecule
(d) An increase in systolic intracellular calcium levels
(e) A block of sodium/calcium exchange
Ans: D

36. A patient has been taking digoxin for several years for chronic heart failure is about to receive atropine for another condition. A common effect of digoxin (at
therapeutic blood levels) that can be almost entirely blocked by atropine is
(a) Decreased appetite
(b) Increased atrial contractility
(c) Increased PR interval on the ECG
(d) Headaches
(e) Tachycardia
Ans: C

37. In a patient given a cardiac glycoside, important effects of the drug on the heart include which of the following?
(a) Decreased atrioventricular conduction velocity
(b) Decreased ejection time
(c) Increased ectopic automaticity
(d) Increased ectopic automaticity
(e) All of the above
Ans: E

38. Which of the following situations constitutes an added risk of digoxin toxicity ?
(a) Starting administration of captopril
(b) Starting administration of quinidine
(c) Hyperkalemia
(d) Hypermagnesemia
(e) Hypocalcemia
Ans: B

39. At rest, the interior of the typical mammalian neuronal axon potential is approximately ________ mV
(a) 0
(b) –70
(c) –100
(d) –20
Ans: B

40. Following enzyme is involved in the synthesis of actylcholine
(a) Choline acetyl transferase
(b) Acetyl cholinesterase
(c) Both (a) and (b)
(d) None of the above
Ans: A

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