36- A 60-year-old man was diagnosed last year with adenocarcinoma of the lung, and a 4 cm mass lesion was treated with a right lower lobectomy. He now has an abdominal CT scan that reveals scattered hepatic mass lesions and hilar lymphadenopathy. For several weeks, he has had increasing malaise. A urinalysis reveals marked proteinuria, and a 24 hour urine protein collection is 2.7 g/24hr. His serum urea is 30 mmol/L (2.5 - 7.5) with creatinine of 450 µmol/L (60 - 110). A renal
biopsy is performed, and there is focal deposition of IgG and C3 with a granular pattern. He is most likely to have which of the following conditions?
1) Goodpasture's syndrome
2) Membranous glomerulonephritis
3) Minimal change glomerulonephritis
4) Nodular glomerulosclerosis
5) Rapidly progressive glomerulonephritis
Answers-2
37- Erythropoietin therapy causes
1) Benign intracranial hypertension
2) Myositis
3) Hypotension
4) Seizures
5) Osteoporosis
Answers-4
38- Which of the following is a feature of cystinuria?
1) accumulation of cystine in the kidney
2) a useful response to acidification of urine
3) autosomal dominant inheritance
4) excessive urinary arginine excretion
5) radiolucent urinary calculi
Answers-4
39- A 19-year-old female developed pleural effusions, ascites and ankle swelling. Her blood pressure was 112/76 mmHg.
Investigations revealed:
serum alanine transferase 17 U/L (5 - 15)
serum total bilirubin 17 umol/L (1 - 22)
serum albumin 21 g/L (34 - 94)
serum total cholesterol 9.8 mmol/L (<5.2)
What is the next most appropriate investigation?
1) Antinuclear antibody
2) Pregnancy test
3) Prothrombin time
4) Serum protein electrophoresis
5) Urinary protein estimation
Answers-5
40- A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement.
serum sodium 140 mmol/L (137 - 144)
serum potassium 4.2 mmol/L (3.5 - 4.9)
serum urea 28 mmol/L (2.5 - 7.5)
serum creatinine 280 µmol/L (60 - 110)
Her condition does not improve after several weeks on corticosteroid therapy, so a renal biopsy is performed. The biopsy demonstrates the presence of segmental sclerosis of 3 of 10 glomeruli identified in the biopsy specimen. Immunofluorescence studies and electron microscopy do not reveal evidence for immune deposits. What is the most appropriate advice to give regarding her condition?
1) She has an underlying malignancy
2) She may require a renal transplant in 10 years
3) She will improve if she loses weight
4) She will likely develop a restrictive lung disease
5) She will probably improve with additional corticosteroid therapy
Answers-2
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biopsy is performed, and there is focal deposition of IgG and C3 with a granular pattern. He is most likely to have which of the following conditions?
1) Goodpasture's syndrome
2) Membranous glomerulonephritis
3) Minimal change glomerulonephritis
4) Nodular glomerulosclerosis
5) Rapidly progressive glomerulonephritis
Answers-2
37- Erythropoietin therapy causes
1) Benign intracranial hypertension
2) Myositis
3) Hypotension
4) Seizures
5) Osteoporosis
Answers-4
38- Which of the following is a feature of cystinuria?
1) accumulation of cystine in the kidney
2) a useful response to acidification of urine
3) autosomal dominant inheritance
4) excessive urinary arginine excretion
5) radiolucent urinary calculi
Answers-4
39- A 19-year-old female developed pleural effusions, ascites and ankle swelling. Her blood pressure was 112/76 mmHg.
Investigations revealed:
serum alanine transferase 17 U/L (5 - 15)
serum total bilirubin 17 umol/L (1 - 22)
serum albumin 21 g/L (34 - 94)
serum total cholesterol 9.8 mmol/L (<5.2)
What is the next most appropriate investigation?
1) Antinuclear antibody
2) Pregnancy test
3) Prothrombin time
4) Serum protein electrophoresis
5) Urinary protein estimation
Answers-5
40- A 15-year-old girl was seen by her family physician because of increasing lethargy. She had a recent history of the "flu". Biochemistry tests show that she has renal impairement.
serum sodium 140 mmol/L (137 - 144)
serum potassium 4.2 mmol/L (3.5 - 4.9)
serum urea 28 mmol/L (2.5 - 7.5)
serum creatinine 280 µmol/L (60 - 110)
Her condition does not improve after several weeks on corticosteroid therapy, so a renal biopsy is performed. The biopsy demonstrates the presence of segmental sclerosis of 3 of 10 glomeruli identified in the biopsy specimen. Immunofluorescence studies and electron microscopy do not reveal evidence for immune deposits. What is the most appropriate advice to give regarding her condition?
1) She has an underlying malignancy
2) She may require a renal transplant in 10 years
3) She will improve if she loses weight
4) She will likely develop a restrictive lung disease
5) She will probably improve with additional corticosteroid therapy
Answers-2
More Questions & Answers:-
Page1 Page2 Page3 Page4 Page5 Page6 Page7 Page8 Page9
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