Wednesday 28 October 2015

Freshers Analagesics & Antipyretics Objective Type Questions And Answers

71. Corticosteroids exert anti-inflammatory action by inhibiting the following enzyme
(a) Cycloxygenase
(b) Lipozygenase
(c) Phospholipase - A
(d) Phosphodiesterase
Ans: C

72. Main effect of sulphinpyrazone in hyperuricaemia is
(a) Suppress the symptoms
(b) Promote the elimination of urate
(c) prevent urate synthesis
(d) All of the above
Ans: B

73. Which of the following glucocorticoids has significant mineralocorticoid activity also ?
(a) Hydrocortisone
(b) Triamcinolone
(c) Dexamethasone
(d) Betamethasone
Ans: A

74. Corticosteroid therapy is practically mandatory in the following condition.
(a) Septic shock
(b) Renal transplant
(c) Rheumatoid arthritis
(d) Ulcerative colitis
Ans: B

75. For limiting cerebral edema due to brain tumour, the preferred corticosteroids are betamenthasone/dexamethasone because
(a) They do not cause Na+ and water retention
(b) They are more potent
(c) They can be administered intravenously
(d) They inhibit brain tumours
Ans: A

76. Systemic corticosteroid therapy is not used routinely and is reserved only for severe cases of
(a) Exfoliative dermatitis
(b) Posterior uveitis
(c) Acute rheumatic fever
(d) Hodgkin’s disease
Ans: C

77. The following adverse effect of corticosteroids is due to their mineralocorticoid action
(a) Osteoporosis
(b) Rise in blood pressure
(c) Moon face
(d) Increased susceptibility to infection
Ans: B

78. Which of the following bones is affected more by glucocorticoid induced osteoporosis?
(a) Femur
(b) Humerus
(c) Radius
(d) Lumber vertebra
Ans: D

79. Morphine produces analgesia by acting at
(a) Peripheral pain receptors
(b) A spinal site
(c) Suspraspinal sites
(d) Both (b) and (c)
Ans: B

80. In man sedation caused by morphine is characterized by
(a) Initial excitement
(b) Little or no motor incoordination
(c) Rise in seizure threshold
(d) All of the above
Ans: B

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