1. â-Aminoethylimidazole is?
(a) 2-methyl histamine
(b) Histamine
(c) 2-pyridyl ethylamine
(d) 4-methyl histamine
Ans: B
2. Agents that often cause vasoconstriction include all of the following except
(a) Angiotensin II
(b) Methysergide
(c) PGF2a
(d) Prostacyclin
(e) Thromboxane
Ans: D
3. Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in
inflammatory processes are produced from arachidonic acid by
(a) Cyclooxygenase 1
(b) Cyclooxygenase 2
(c) Glutathione – S – transferase
(d) Lipoxygenase
(e) Phospholipase A2
Ans: B
4. A 60-year-old woman has glaucoma following cataract surgery. Which of the following can be used to reduce intraocular pressure?
(a) Leukotriene LTD4 or its analogs
(b) Prostaglandin E2 or its analogs
(c) Prostaglandin F2a or its analogs
(d) Slow-reacting substance of anaplylaxis (SRS-A)
(e) Thromboxane A2 or its analogs
Ans: C
5. Which of the following is a reversible inhibitor of platelet cyclooxygenase?
(a) Alprostadil
(b) Aspirin
(c) Ibuprofen
(d) LTC4
(e) Misoprostol
Ans: C
6. Vasodilation by prostaglandins involves
(a) Arterioles
(b) Precapillary sphincters
(c) Postcapillary venules
(d) All of the above
Ans: D
7. Fentanyl transdermal patches have been used postoperatively to provide transdermal analgesia. The most dangerous adverse effect of this mode of administration is
(a) Cutaneous reactions
(b) Diarrhea
(c) Hypertension
(d) Relaxation of skeletal muscle
(e) Respiratory depression
Ans: E
8. Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include
(a) Aqueous diffusion
(b) Aqueous hydrolysis
(c) Lipid diffusion
(d) Pinocytosis or endocytosis
(e) Special carrier transport
Ans: E
9. Following is an example of paraaminophenol NSAID
(a) Diclofenac
(b) Acetaminophen
(c) Piroxicam
(d) Celecoxib
Ans: B
10. This drug, which does not activate opioid receptors, has been proposed as a maintenance drug in treatment programs for opioid addicts; a singly oral dose will
block the effects of injected heroin for up to 48 hours
(a) Amphetamine
(b) Buprenorphine
(c) Naloxone
(d) Naltrexone
(e) Propoxyphene
Ans: D
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(a) 2-methyl histamine
(b) Histamine
(c) 2-pyridyl ethylamine
(d) 4-methyl histamine
Ans: B
2. Agents that often cause vasoconstriction include all of the following except
(a) Angiotensin II
(b) Methysergide
(c) PGF2a
(d) Prostacyclin
(e) Thromboxane
Ans: D
3. Inflammation is a complex tissue reaction that includes the release of cytokines, leukotrienes, prostaglandins, and peptides. Prostaglandins involved in
inflammatory processes are produced from arachidonic acid by
(a) Cyclooxygenase 1
(b) Cyclooxygenase 2
(c) Glutathione – S – transferase
(d) Lipoxygenase
(e) Phospholipase A2
Ans: B
4. A 60-year-old woman has glaucoma following cataract surgery. Which of the following can be used to reduce intraocular pressure?
(a) Leukotriene LTD4 or its analogs
(b) Prostaglandin E2 or its analogs
(c) Prostaglandin F2a or its analogs
(d) Slow-reacting substance of anaplylaxis (SRS-A)
(e) Thromboxane A2 or its analogs
Ans: C
5. Which of the following is a reversible inhibitor of platelet cyclooxygenase?
(a) Alprostadil
(b) Aspirin
(c) Ibuprofen
(d) LTC4
(e) Misoprostol
Ans: C
6. Vasodilation by prostaglandins involves
(a) Arterioles
(b) Precapillary sphincters
(c) Postcapillary venules
(d) All of the above
Ans: D
7. Fentanyl transdermal patches have been used postoperatively to provide transdermal analgesia. The most dangerous adverse effect of this mode of administration is
(a) Cutaneous reactions
(b) Diarrhea
(c) Hypertension
(d) Relaxation of skeletal muscle
(e) Respiratory depression
Ans: E
8. Opioid analgesics are either contraindicated or must be used with extreme caution in several clinical situations. For morphine, such situations do not include
(a) Aqueous diffusion
(b) Aqueous hydrolysis
(c) Lipid diffusion
(d) Pinocytosis or endocytosis
(e) Special carrier transport
Ans: E
9. Following is an example of paraaminophenol NSAID
(a) Diclofenac
(b) Acetaminophen
(c) Piroxicam
(d) Celecoxib
Ans: B
10. This drug, which does not activate opioid receptors, has been proposed as a maintenance drug in treatment programs for opioid addicts; a singly oral dose will
block the effects of injected heroin for up to 48 hours
(a) Amphetamine
(b) Buprenorphine
(c) Naloxone
(d) Naltrexone
(e) Propoxyphene
Ans: D
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