Wednesday 28 October 2015

Tricky Drugs Used in Respiratory Objective Type Questions And Answers

41. Tachyphylaxis to many actions on repeated injection is a feature of the following autocoid
(a) Histamine
(b) 5-Hydroxytryptamine
(c) Bradykinin
(d) Angiotensin
Ans: B

42. The smooth muscle stimulating action of 5-HT is most marked in the
(a) Bronchi
(b) Intestines
(c) Ureter
(d) Billary tract
Ans: B

43. The 5-HT antagonist that has antihypertensive property is
(a) Methysergide
(b) Cyproheptadine
(c) Ketanserin
(d) Ondansetron
Ans: C

44. The most important receptor involved in cytotoxic drug induced vomiting is
(a) Histamine H1 receptor
(b) Serotonin 5-HT3 receptor
(c) Dopamine D2 receptor
(d) Opioid ยต receptor
Ans: B

45. Which of the following expectorants acts both directly on the airway mucosa as well as reflexly ?
(a) Potassium iodide
(b) Guaiphenesin
(c) Terpin hydrate
(d) Bromhexine
Ans: A

46. Bromhexine acts by 
(a) Inhibiting cough center
(b) Irritating gastric mucosa and reflexly increasing bronchial secretion
(c) Depolymerizing mucopolysaccharides present
(d) Desensitizing stretch receptors in the lungs
Ans: C

47. The primary goals of asthma therapy include all of the following except
(a) maintain normal activity levels
(b) maintain control of symptoms
(c) avoid adverse effects of asthma medications
(d) prevent acute exacerbations and chronic symptoms
(e) prevent destruction of lung tissue
Ans: E

48. Antitussives act by
(a) Liquifying bronchial secretions
(b) Raising the threshold of cough centre
(c) Reducing cough inducing impulses from the lungs
(d) Both (b) and (c)
Ans: D

49. Which of the following antitussive is present in opium but has no analgesic or addicting properties ?
(a) Noscapine
(b) Codeine
(c) Pholcodeine
(d) Ethylmorphine
Ans: A

50. Bronchodilators are useful in cough
(a) Only when cough is non-productive
(b) Only when cough is associated with thick sticky secretions
(c) Only when reflex bronchoconstriction is associated
(d) Irrespective of nature of cough or associated features
Ans: C

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