61. The most consistent, pronounced and sustained relief of symptoms in chronic bronchial asthma is afforded by
(a) ß2 sympathomimetics
(b) Anticholinergics
(c) Sodium cromoglycate
(d) Corticosteroids
Ans: D
62. Intransasal spray of budesonide is indicated in
(a) Common cold
(b) Acute vasomotor rhinitis
(c) Perennial vasomotor rhinitis
(d) Epistaxis
Ans: C
63. In patients of bronchial asthma inhaled corticosteroids achieve the following except
(a) Reduce the need for bronchodilator medication
(b) Control an attack of refractory asthma
(c) Reduce bronchial hyperreactivity
(d) Reverse diminished responsiveness to sympathomimetic bronchodilators
Ans: B
64. Budesonide is a
(a) Nonsteroidal anti-inflammatory drug
(b) High ceiling diuretic
(c) Inhaled corticosteroid for asthma
(d) Contraceptive
Ans: C
65. In an asthma patient treated with systemic corticosteroids, bronchodilator drugs
(a) Are not needed
(b) Are contraindicated
(c) May be used on ‘as and when required’ basis
(d) Are ineffective
Ans: C
66. To be a useful inhaled glucocorticoid the drug should have
(a) High oral bioavailability
(b) Low oral bioavailability
(c) Additional bronchodilator activity
(d) Prodrug character
Ans: B
67. Histamine
(a) May be released from mast cells by a number of therapeutic agents
(b) Causes sedation
(c) Decreases the force of contraction of ventricular muscle
(d) Can cause strong contractions of the gravid human uterus
Ans: D
68. Chronic Bronchitis is characterized by
I. the distruction of central and peripheral portions of the acinus
II. an increased number of mucous glands and goblet cells
III. edema and inflammation of the bronchioles
(a) only I is correct
(b) only III is correct
(c) I and II are correct
(d) II and III are correct
(e) I, II and III are correct
Ans: C
69. Smooth muscle relaxation is due to stimulation of which type of histamine receptors
(a) H1
(b) H2
(c) H3
(d) All of the above
Ans: B
70. All the following are employed in inhalation therapy of asthma except
(a) Beclomethasone
(b) Budesonide
(c) Dexamethasone
(d) Triamcinolone
Ans: C
71. Which xanthine derivative has no function in asthma ?
(a) Theophylline
(b) Pentoxyphyllin
(c) Enprofylin
(d) None of the above
Ans: B
72. What is symport ?
(a) Counter transport
(b) Contransport
(c) Carrier mediated diffusion
(d) Solvent drug
Ans: B
73. Pyridostigmine differs from neostigmine in that
(a) More potent orally
(b) Longer acting
(c) Less muscarinic side effects
(d) All of the above
Ans: B
(a) ß2 sympathomimetics
(b) Anticholinergics
(c) Sodium cromoglycate
(d) Corticosteroids
Ans: D
62. Intransasal spray of budesonide is indicated in
(a) Common cold
(b) Acute vasomotor rhinitis
(c) Perennial vasomotor rhinitis
(d) Epistaxis
Ans: C
63. In patients of bronchial asthma inhaled corticosteroids achieve the following except
(a) Reduce the need for bronchodilator medication
(b) Control an attack of refractory asthma
(c) Reduce bronchial hyperreactivity
(d) Reverse diminished responsiveness to sympathomimetic bronchodilators
Ans: B
64. Budesonide is a
(a) Nonsteroidal anti-inflammatory drug
(b) High ceiling diuretic
(c) Inhaled corticosteroid for asthma
(d) Contraceptive
Ans: C
65. In an asthma patient treated with systemic corticosteroids, bronchodilator drugs
(a) Are not needed
(b) Are contraindicated
(c) May be used on ‘as and when required’ basis
(d) Are ineffective
Ans: C
66. To be a useful inhaled glucocorticoid the drug should have
(a) High oral bioavailability
(b) Low oral bioavailability
(c) Additional bronchodilator activity
(d) Prodrug character
Ans: B
67. Histamine
(a) May be released from mast cells by a number of therapeutic agents
(b) Causes sedation
(c) Decreases the force of contraction of ventricular muscle
(d) Can cause strong contractions of the gravid human uterus
Ans: D
68. Chronic Bronchitis is characterized by
I. the distruction of central and peripheral portions of the acinus
II. an increased number of mucous glands and goblet cells
III. edema and inflammation of the bronchioles
(a) only I is correct
(b) only III is correct
(c) I and II are correct
(d) II and III are correct
(e) I, II and III are correct
Ans: C
69. Smooth muscle relaxation is due to stimulation of which type of histamine receptors
(a) H1
(b) H2
(c) H3
(d) All of the above
Ans: B
70. All the following are employed in inhalation therapy of asthma except
(a) Beclomethasone
(b) Budesonide
(c) Dexamethasone
(d) Triamcinolone
Ans: C
71. Which xanthine derivative has no function in asthma ?
(a) Theophylline
(b) Pentoxyphyllin
(c) Enprofylin
(d) None of the above
Ans: B
72. What is symport ?
(a) Counter transport
(b) Contransport
(c) Carrier mediated diffusion
(d) Solvent drug
Ans: B
73. Pyridostigmine differs from neostigmine in that
(a) More potent orally
(b) Longer acting
(c) Less muscarinic side effects
(d) All of the above
Ans: B
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