31. Fall in blood pressure caused by larger doses of histamine is blocked by
(a) H1 antihistaminics alone
(b) H2 ANTAgonists alone
(c) Combination of H1 and H2 antagonists
(d) None of the above
Ans: C
32. Histamine is involved as a mediator in the following pathological conditon
(a) Cocaine
(b) Dibucaine
(c) Lidocaine
(d) Procaine
Ans: B
33. In the emergency department, the preferred first-line therapy for asthma exacerbation is
(a) Theophylline
(b) A ß-agonist
(c) A corticosteroid
(d) Cromolyn sodium
(e) An antihistamine
Ans: B
34. The capacity of an antihistaminic to produce sedation depends on the following except
(a) Relative affinity for central versus peripheral H1 receptors
(b) Ability to penetrate blood-brain barrier
(c) Individual susceptibility
(d) Ratio of H1 : H2 blockade produced by the drug
Ans: D
35. While prescribing the conventional H1 antihistaminics the patient should be advised to avoid
(a) Driving motor vehicles
(b) Consuming processed cheese
(c) Strenuous physical exertion
(d) All of the above
Ans: A
36. The antihistaminc which has calcium channel blocking and labyrinthine suppressant property is
(a) Cyproheptadine
(b) Cinnarizine
(c) Clemastine
(d) Cetirizine
Ans: B
37. Erythromycin should not be given to patient being treated with terfenadine because
(a) Erythromycin induces the metabolism of terfenadine
(b) Dangerous ventricular arrhythmias can occur
(c) Terfenadine inhibits metabolism of erythromycin
(d) Terfenadine antagonizes the antimicrobal action of erythromycin
Ans: B
38. Select the H1 antihistaminic which is used topically in the nose for allergic rhinitis
(a) Deep intra-abdominal operation
(b) Trachial intubation
(c) Tetanus
(d) Diagonosis of myasthenia gravis
Ans: D
39. H1 antihistaminics are beneficial in
(a) All types of allergic disorders
(b) Certain type I allergic reactions only
(c) Anaphylactic shock(d) Bronchial asthma
Ans: B
40. The action of 5-Hydroxy tryptamine mediated by the 5-HT3 receptor is
(a) Vasoconstriction
(b) Bradycardia
(c) EDRF release
(d) Platelet aggregation
Ans: B
(a) H1 antihistaminics alone
(b) H2 ANTAgonists alone
(c) Combination of H1 and H2 antagonists
(d) None of the above
Ans: C
32. Histamine is involved as a mediator in the following pathological conditon
(a) Cocaine
(b) Dibucaine
(c) Lidocaine
(d) Procaine
Ans: B
33. In the emergency department, the preferred first-line therapy for asthma exacerbation is
(a) Theophylline
(b) A ß-agonist
(c) A corticosteroid
(d) Cromolyn sodium
(e) An antihistamine
Ans: B
34. The capacity of an antihistaminic to produce sedation depends on the following except
(a) Relative affinity for central versus peripheral H1 receptors
(b) Ability to penetrate blood-brain barrier
(c) Individual susceptibility
(d) Ratio of H1 : H2 blockade produced by the drug
Ans: D
35. While prescribing the conventional H1 antihistaminics the patient should be advised to avoid
(a) Driving motor vehicles
(b) Consuming processed cheese
(c) Strenuous physical exertion
(d) All of the above
Ans: A
36. The antihistaminc which has calcium channel blocking and labyrinthine suppressant property is
(a) Cyproheptadine
(b) Cinnarizine
(c) Clemastine
(d) Cetirizine
Ans: B
37. Erythromycin should not be given to patient being treated with terfenadine because
(a) Erythromycin induces the metabolism of terfenadine
(b) Dangerous ventricular arrhythmias can occur
(c) Terfenadine inhibits metabolism of erythromycin
(d) Terfenadine antagonizes the antimicrobal action of erythromycin
Ans: B
38. Select the H1 antihistaminic which is used topically in the nose for allergic rhinitis
(a) Deep intra-abdominal operation
(b) Trachial intubation
(c) Tetanus
(d) Diagonosis of myasthenia gravis
Ans: D
39. H1 antihistaminics are beneficial in
(a) All types of allergic disorders
(b) Certain type I allergic reactions only
(c) Anaphylactic shock(d) Bronchial asthma
Ans: B
40. The action of 5-Hydroxy tryptamine mediated by the 5-HT3 receptor is
(a) Vasoconstriction
(b) Bradycardia
(c) EDRF release
(d) Platelet aggregation
Ans: B
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