51 The common and dose related side effect of salbutamol is
(a) Rise in blood pressure
(b) Muscle tremor
(c) Hyperglycaemia
(d) Central nervous system stimulation
Ans: B
52. Which of the following tests is used at home to assess therapy and determine if a patient with asthma should seek emergency care?
(a) Forced expiratory volume in one second (FEV1)
(b) Forced vital capacity (FVC)
(c) Total lung capacity (TLC)
(d) Peak expiratory flow rate (PEFR)
(e) Residual volume (RV)
Ans: D
53. In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s).
(a) Inhibits antigen-antibody reaction in the lungs
(b) Causes bronchodilatation
(c) Reduces bronchial hyperreactivity
(d) Both (b) and (c)
Ans: B
54. Select the correct statement about salmeterol.
(a) It is a long acting selective ß2 agonist bronchodilator
(b) It is a bronchodilator with anti-inflammatory property
(c) It is a ß blocker that can be safely given to asthmatics
(d) It is an antihistaminic with mast cells stabilizing property
Ans: A
55. Caffeine is more powerful than theophylline in exerting the following action
(a) Bronchodilatation
(b) Cardiac stimulation
(c) Diuresis
(d) Augmentation of skeletal muscle contractility
Ans: D
56. Methylxanthines exert the following action (s) at cellular/molecular level
(a) Intracellular release of Ca2+
(b) Antagonism of adenosine
(c) Inhibition of phosphodiesterase
(d) All of the above
Ans: D
57. Relatively higher dose of theophylline is required to attain therapeutics plasma concentration in
(a) Smokers
(b) Congestive heart failure patients
(c) Those receiving erythromycin
(d) Those receiving cimetidine
Ans: A
58. The antiasthma drug which cannot be administered by inhalation is
(a) Theophylline
(b) Ipratropium bromide
(c) Budesonide
(d) Terbutaline
Ans: A
59. A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ?
(a) Oral salbutamol
(b) Oral theophylline
(c) Inhaled sodium cromoglycate
(d) Inhaled beclomethasone dipropionate
Ans: C
60. Which of the following drugs is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity ?
(a) Sodium cromoglycate
(b) Ketotifen
(c) Beclomethasone dipropionate
(d) Mepyramine maleate
Ans: B
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(a) Rise in blood pressure
(b) Muscle tremor
(c) Hyperglycaemia
(d) Central nervous system stimulation
Ans: B
52. Which of the following tests is used at home to assess therapy and determine if a patient with asthma should seek emergency care?
(a) Forced expiratory volume in one second (FEV1)
(b) Forced vital capacity (FVC)
(c) Total lung capacity (TLC)
(d) Peak expiratory flow rate (PEFR)
(e) Residual volume (RV)
Ans: D
53. In a patient of bronchial asthma, inhaled salbutamol produces the following effect(s).
(a) Inhibits antigen-antibody reaction in the lungs
(b) Causes bronchodilatation
(c) Reduces bronchial hyperreactivity
(d) Both (b) and (c)
Ans: B
54. Select the correct statement about salmeterol.
(a) It is a long acting selective ß2 agonist bronchodilator
(b) It is a bronchodilator with anti-inflammatory property
(c) It is a ß blocker that can be safely given to asthmatics
(d) It is an antihistaminic with mast cells stabilizing property
Ans: A
55. Caffeine is more powerful than theophylline in exerting the following action
(a) Bronchodilatation
(b) Cardiac stimulation
(c) Diuresis
(d) Augmentation of skeletal muscle contractility
Ans: D
56. Methylxanthines exert the following action (s) at cellular/molecular level
(a) Intracellular release of Ca2+
(b) Antagonism of adenosine
(c) Inhibition of phosphodiesterase
(d) All of the above
Ans: D
57. Relatively higher dose of theophylline is required to attain therapeutics plasma concentration in
(a) Smokers
(b) Congestive heart failure patients
(c) Those receiving erythromycin
(d) Those receiving cimetidine
Ans: A
58. The antiasthma drug which cannot be administered by inhalation is
(a) Theophylline
(b) Ipratropium bromide
(c) Budesonide
(d) Terbutaline
Ans: A
59. A 10 year old child suffers from exercise induced asthma: Which is the most suitable first line drug for regular prophylactic therapy ?
(a) Oral salbutamol
(b) Oral theophylline
(c) Inhaled sodium cromoglycate
(d) Inhaled beclomethasone dipropionate
Ans: C
60. Which of the following drugs is neither bronchodilator nor anti-inflammatory, but has antihistaminic and mast cell stabilizing activity ?
(a) Sodium cromoglycate
(b) Ketotifen
(c) Beclomethasone dipropionate
(d) Mepyramine maleate
Ans: B
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