Monday 26 October 2015

Molecular Biology Multiple Choice Questions And Answers

11- The thyroid hormone receptor is:
1) A gated ion channel
2) A cell surface receptor
3) A cytoplasmic protein
4) A G-protein coupled receptor
5) A nuclear receptor
Answers-5
The thyroid hormone receptor is a nuclear receptor. When it binds T3 it is able to bind to the thyroid hormone response element (TRE) in the promoter region of
thyroid hormone responsive genes and initiates transcription.

12- Proteins known as cyclins:
1) Regulate the menstrual cycle
2) Are differentially expressed throughout the cell cycle
3) Regulate antibody production
4) Regulate the cycling of receptors between the cell surface and the cytoplasm
5) Regulate DNA transcription
Answers-2
Cyclins are key regulators of the cell cycle, different cyclins are expressed at different stages of the cell cycle.

13- Which of the following is a glycoprotein hormone?
1) Growth hormone releasing hormone
2) Cortisol
3) Thyrotropin releasing hormone (TRH)
4) Thyrotropin (TSH)
5) Oxytocin
Answers-4
Thyrotropin is glycosylated, cortisol is a steroid hormone and the others are peptide hormones/neuropeptides which as a group are rarely glycosylated.

14- Which ONE of the following have their own self replicating DNA?
1) Golgi body
2) Lysosomes
3) mitochondria
4) Peroxisome
5) Rough Endoplasmic Reticulum
Answers-3
Abnormalities of Mitochondrial DNA are associated with inherited conditions such as Leber's OA, MELAS syndrome and DIDMOAD(Dr Vajira H. W. Dissanayake)

15- A Plasmid is best described as
1) a recombinant section of DNA
2) a small viral particle
3) bacterial DNA separate from the chromosome
4) consist of multiple copies of a single gene
5) having multiple origins of replication
Answers-3

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