Monday 26 October 2015

23 Top Molecular Biology Objective Type Questions And Answers

1- Apoptosis is induced by:
1) Activation of caspases
2) The MAP kinase pathway
3) DNA synthesis
4) Antibodies
5) Necrosis
Answers-1

2- Phosphorylation of protein tyrosine residues is associated with:
1) Cell signalling pathways
2) Protein degradation
3) Alzheimer's disease
4) Protein synthesis
5) Creutzfeldt-Jacob Disease
Answers-1
Phosphorylation of specific tyrosine residues of components of cell signalling pathways is often a key event in the activation of the pathway.

3- Two strains of Escherichia coli are isolated and both are resistant to ampicillin. Strain A retains its resistance to amplicillin when grown form multiple generations in the absence of ampicillin. However strain B loses its resistance when grown in the absence of ampicillin. Which of the following best explains the loss of antibiotic resistance in strain B?
1) Changes in the bacterial DNA gyrase
2) Downregulation of the resistance gene
3) Loss of a plasmid containing the resistance gene
4) Mutations in the resistance gene
5) Transposition of another sequence into the resistance gene
Answers-3

4- Apoptosis is the process of programmed cell death and occurs in cells that have damaged DNA. A mediator of this process is a tumour suppressor gene that inhibits mitosis and promotes apoptosis. This gene is:-
1) bcl-2
2) caspases
3) fas (CD95)
4) p53
5) ras
Answers-4

5- Which of the following is an oncogene?
1) The N-Myc gene
2) The WT1 (first Wilm's tumour) gene
3) The Retinoblastoma gene
4) The WT2 (second Wilm's tumour) gene
5) The BCRabI translocation (Philadelphia chromosome)
Answers-1

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