11- A 28 year old male presents with a four day history of profuse bloody diarrhoea after returning from a holiday in the Far East. Which of the following regarding his illness is true?
1) a negative amoebic fluorescent antibody test excludes a diagnosis of acute amoebic dysentry
2) Cysts to E. histolytica in the stools confirms a diagnosis of acute amoebic dysentry
3) cholera is a likely diagnosis
4) Giardiasis is a likely diagnosis
5) shigellosis is a likely diagnosis
Answers-5
12- A 63 year old patient with known alcohol related cirrhosis presented with ascites, abdominal tenderness and peripheral oedema. A diagnostic tap revealed a neutrophil count of 400/mm3 (normal <250mm3).
Which of the following would be of most immediate benefit?
1) fluid restriction and a no added salt diet
2) intravenous antibiotics
3) oral spironolactone
4) therapeutic paracentesis
5) trans-jugular intrahepatic porto-systemic shunt
Answers-2
13- A 29-year-old man presents with anaemia, bleeding tendency, diarrhoea and abdominal pain. Examination reveals a palpable mass in the right lower quadrant and anal skin tags. What is the most likely underlying condition?
1) chronic pancreatitis
2) coeliac disease
3) crohn's disease
4) intestinal lymphoma
5) ulcerative colitis
Answers-3
14- Ten individuals are admitted to casualty with profuse vomiting after attending a retirement dinner in a chinese restaurant. They all ate at roughly 7 pm and became ill at roughly midnight. Nine ate a mixture of dishes except one female who ate vegetarian dishes with her rice. What is the most likely infective organism?
1) Salmonella enteriditis
2) Staphylococcus aureus
3) E. Coli
4) Clostridium perfringens
5) Bacillus cereus
Answers-5
15- Which of the following is activated by Cholera toxin?
1) Adenylate cyclase
2) Guanlyate cyclase
3) Peroxisome proliferator receptor (PPAR) gamma
4) Sodium/potassium ATPase
5) The glucose-sodium transporter
Answers-1
16- Which of the following is NOT true of a patient with ascites due to liver cirhosis:
1) Spontaneous bacterial peritonitis is a recognised feature
2) The usual source of the ascitic fluid is mainly from the exudation from the surface of the liver
3) Hepatic intrasinusoidal pressure is elevated
4) Urinary sodium concentration is usually less than 10 mmol/l
5) Cardiac output is often elevated
Answers-2
17- A 35-year-old woman with a history of recurrent anaemia was noted to have target cells and Howell-Jolly bodies on a blood film examination. Investigations revealed:
Haemoglobin 7.0 g/dL (11.3-16.5)
MCV 77 fl (80-96)
MCH 26.2 pg (28-32)
Serum B12 140 ug/L (160-760)
Red cell folate 95 ug/L (160-640)
Serum ferritin 10 ug/L (15-300)
What disease specific antibody is most likely to be present?
1) Anti-endomysial
2) Anti-gastric parietal cell
3) Anti-glutamic acid decarboxylase
4) Anti-intrinsic factor
5) Antimitochondrial
Answers-1
18- Which one of the following is a feature of the VIPoma syndrome?
1) Alkalosis
2) Hypoglycaemia
3) Hypokalaemia
4) Increased gastric acid seceretion
5) Provocation of VIP release by somatostatin
Answers-3
19- A 40 year old single man returned from holiday in Europe with mild bloody diarrhoea which had lasted for two weeks. He had lost 2.5 kg in weight, had occasional lower abdominal cramping discomfort and a painful swelling of his left knee.
What is the most likely diagnosis?
1) amoebiasis
2) campylobacter infection
3) Crohn's disease
4) gonococcal septicaemia
5) ulcerative colitis
Answers-2
20- A 43 year old male presents with weight loss and watery diarrhoea. Investigations reveal hypokalaemia with a pancreatic mass. Which of the following would support the diagnosis of a VIPoma?
1) Achlorhydria
2) Hypoglycaemia
3) Increased Pancreatic polypeptide
4) Migratory erythema
5) Pellagra
Answers-1
More Questions & Answers:-
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1) a negative amoebic fluorescent antibody test excludes a diagnosis of acute amoebic dysentry
2) Cysts to E. histolytica in the stools confirms a diagnosis of acute amoebic dysentry
3) cholera is a likely diagnosis
4) Giardiasis is a likely diagnosis
5) shigellosis is a likely diagnosis
Answers-5
12- A 63 year old patient with known alcohol related cirrhosis presented with ascites, abdominal tenderness and peripheral oedema. A diagnostic tap revealed a neutrophil count of 400/mm3 (normal <250mm3).
Which of the following would be of most immediate benefit?
1) fluid restriction and a no added salt diet
2) intravenous antibiotics
3) oral spironolactone
4) therapeutic paracentesis
5) trans-jugular intrahepatic porto-systemic shunt
Answers-2
13- A 29-year-old man presents with anaemia, bleeding tendency, diarrhoea and abdominal pain. Examination reveals a palpable mass in the right lower quadrant and anal skin tags. What is the most likely underlying condition?
1) chronic pancreatitis
2) coeliac disease
3) crohn's disease
4) intestinal lymphoma
5) ulcerative colitis
Answers-3
14- Ten individuals are admitted to casualty with profuse vomiting after attending a retirement dinner in a chinese restaurant. They all ate at roughly 7 pm and became ill at roughly midnight. Nine ate a mixture of dishes except one female who ate vegetarian dishes with her rice. What is the most likely infective organism?
1) Salmonella enteriditis
2) Staphylococcus aureus
3) E. Coli
4) Clostridium perfringens
5) Bacillus cereus
Answers-5
15- Which of the following is activated by Cholera toxin?
1) Adenylate cyclase
2) Guanlyate cyclase
3) Peroxisome proliferator receptor (PPAR) gamma
4) Sodium/potassium ATPase
5) The glucose-sodium transporter
Answers-1
16- Which of the following is NOT true of a patient with ascites due to liver cirhosis:
1) Spontaneous bacterial peritonitis is a recognised feature
2) The usual source of the ascitic fluid is mainly from the exudation from the surface of the liver
3) Hepatic intrasinusoidal pressure is elevated
4) Urinary sodium concentration is usually less than 10 mmol/l
5) Cardiac output is often elevated
Answers-2
17- A 35-year-old woman with a history of recurrent anaemia was noted to have target cells and Howell-Jolly bodies on a blood film examination. Investigations revealed:
Haemoglobin 7.0 g/dL (11.3-16.5)
MCV 77 fl (80-96)
MCH 26.2 pg (28-32)
Serum B12 140 ug/L (160-760)
Red cell folate 95 ug/L (160-640)
Serum ferritin 10 ug/L (15-300)
What disease specific antibody is most likely to be present?
1) Anti-endomysial
2) Anti-gastric parietal cell
3) Anti-glutamic acid decarboxylase
4) Anti-intrinsic factor
5) Antimitochondrial
Answers-1
18- Which one of the following is a feature of the VIPoma syndrome?
1) Alkalosis
2) Hypoglycaemia
3) Hypokalaemia
4) Increased gastric acid seceretion
5) Provocation of VIP release by somatostatin
Answers-3
19- A 40 year old single man returned from holiday in Europe with mild bloody diarrhoea which had lasted for two weeks. He had lost 2.5 kg in weight, had occasional lower abdominal cramping discomfort and a painful swelling of his left knee.
What is the most likely diagnosis?
1) amoebiasis
2) campylobacter infection
3) Crohn's disease
4) gonococcal septicaemia
5) ulcerative colitis
Answers-2
20- A 43 year old male presents with weight loss and watery diarrhoea. Investigations reveal hypokalaemia with a pancreatic mass. Which of the following would support the diagnosis of a VIPoma?
1) Achlorhydria
2) Hypoglycaemia
3) Increased Pancreatic polypeptide
4) Migratory erythema
5) Pellagra
Answers-1
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