Freshers Immunology Multiple Choice Questions and answers

51. Eczema in an infant most commonly occurs in/on the:
A. Antecubitutal and Popliteal fossae
B. Perineal region
C. Scalp and flexural areas
D. Extensor surface of arm and legs
E. All of the above
 Ans: C

52. As part of the work up of adult asthma, which of the following reproducible, pre and post bronchodilator pulmonary function test results would be interpreted as showing significant reversibility?
A. a 15% increase in FEF 25-75%
B. a 15% increase in FEV1 (425 ml improvement)
C. a 20% increase in FEV1 (180 ml improvement)
D. a 15% increase in FEV1/FVC ratio
E. a 15% increase in FVC
 Ans: B

53. All of the following medications can affect late phase (including by prophylaxis of the immediate allergic response) response in asthma except:
A. Corticosteroids
B. Leukotriene modifiers
C. Cromolyn sodium
D. Albuterol
E. There is no such medication in the list
 Ans: D

54. Drug of choice for uncomplicated acute urticaria is:
A. Corticosteroid
B. Antihistamines (H2 type)
C. Antihistamines (H1 type)
D. Subcutaneous terbutaline
E. All of the above
 Ans: C

55. Reasonable recommendations for a patient with moderate persistent asthma poorly controlled on low dose inhaled corticosteroids include all except:
A. Add salmeterol inhaler BID
B. Double the dose of inhaled corticosteroid
C. Add a leukotriene modifier
D. Add nebulized cromolyn BID
E. All answers are correct
 Ans: D

56. Which of the following is a clear indication for penicillin allergy skin testing:
A. A 40-year-old patient with a history of anaphylaxis after ampicillin ten
years ago. The patient now has endocarditis. Culture is positive for a
streptococcal organism sensitive only to penicillin.
B. A 26-year-old patient with a history of Steven-Johnson’s Syndrome after
receiving amoxicillin.
C. A 65-year-old ICU patient receiving penicillin and vancomycin with
flushing and hypotension.
D. A 39-year-old female who, eleven days after taking penicillin for a strep
pharyngitis, develops angioedema, arthralgias, urticaria and a low grade
fever.
E. All of the above.
 Ans: A

57. The major advantage of second generation antihistamines is:
A. They do cross the blood brain barrier and help patients to relax
B. They are very long acting
C. They cause decongestion as well as decreasing rhinorrhea
D. They minimally cross the blood brain barrier and have a decreased sedation
effect
E. They decrease appetite
 Ans: D

58. Which of the following types of infection are increased in patients with humoral or B-cell immune deficiencies?
A. Sinusitis
B. Otitis media
C. Pneumonia
D. Meningitis
E. All of the above
 Ans: E

59. The most common cause of chronic urticaria, especially in adults, is:
A. Food allergy
B. Connective tissue disease
C. Drug allergy
D. Idiopathic
E. Viral infections
 Ans: A

60. Congenital absence of the late complement components (C5, C6, C7, C8) is most often associated with:
A. Viral infections
B. Recurrent Neisserial infections
C. Lupus-like disease
D. Candidiasis
E. Delayed separation of the umbilical cord
 Ans: B

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