Monday 26 October 2015

8 Top New Drugs Objective Type Questions And Answers

1-Which of the following is a metabolic effect of exenatide?
1) accelerates gastric emptying
2) improves insulin sensitivity
3) inhibits insulin release
4) promotes gluconeogenesis by the liver
5) suppresses appetite
Answer-5

2-Which of the following are recognised side effects associated with the use of rimonabant?
1) Benign intracranial hypertension
2) Depression
3) QT prolongation
4) Steven's Johnson syndrome
5) Visual field defects
Answer-2

3-A 58-year-old woman presents with early features of COPD. She is a heavy smoker and asks about drugs that may help her to stop smoking. In particular, she has heard about a new drug that is now available called Champix (varenicline). Varenicline is an agent used in the treatment of smokers to help them quit. Which of the following best describes its mechanism of action?
1) An a2-noradrenergic agonist that suppresses sympathetic activity
2) Is a nicotine replacement therapy
3) Is a partial agonist of the alpha4beta2 nicotinic receptor
4) A tricyclic antidepressant with mostly noradrenergic properties
5) Reduces uptake of dopamine, serotonin and norepinephrine
Answer-3

4-In a study, healthy volunteers are given 50 mls of 50% dextrose solution by one of two routes. Route A is intravenous and Route B is via a nasogastric tube. Every 15 minutes the plasma insulin level and glucose is measured and plotted on a graph. Which of the following statements would best describe the likely results comparing Route A to Route B in this experiment?
1) insulin higher, glucose higher in Route A
2) insulin higher, glucose higher in Route B
3) insulin higher, glucose lower in Route A
4) insulin higher, glucose lower in Route B
5) insulin and glucose the same in Route A and Route B
Answer-4


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1 comment:

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