1- A randomised double-blind placebo controlled study of a cholesterollowering drug in the primary prevention of coronary heart disease was conducted over a five-year follow up period. The absolute risk of myocardial infarction in the group-receiving placebo during this time was 10 per cent.
The relative risk of those given the cholesterol lowering medication was 0.8.
What number of patients will need to be treated with active drug for five years to prevent one myocardial infarction?
1) 20
2) 40
3) 50
4) 80
5) 100
Answers-3
2- Regarding standard error of the mean (SEM) and standard deviation (SD) the following ONE statement is true
1) Standard error of mean is calculated by taking the square root of the standard deviation of the sample means
2) Standard deviation invariably falls with increasing sample size
3) Standard error of mean increases with sample size
4) if standard deviation is greater than the mean the distribution is negatively skewed
5) Student's t test is a non-parametric test
Answers-4
3- A publication describes a new diagnostic test for myocardial infarction. You want to know what proportion of patients with a confirmed myocardial infarction will be identified by the test.
Which one of the following measurements would indicate this?
1) Accuracy
2) Negative predictive value
3) Positive predictive value
4) Sensitivity
5) Specificity
Answers-4
4- In a trial of a new drug the following results were obtained:
improved not improved
treatment group 44 16
placebo group 36 26
Which of the following statements regarding the statistical analysis or interpretation of the trial is true?
1) A Student t-test could be used.
2) Pearson's coefficient of linear regression would be an appropriate significance test.
3) The data could be evaluated using the Chi-squared test.
4) The numbers are too small to draw any conclusions.
5) The results so obviously show the benefit of treatment that statistical analysis is not required.
Answers-3
5- A new antihypertensive drug needs to be investigated to establish its relative potency.
Which of the following techniques is most appropriate for this purpose?
1) bioassay
2) case-control study
3) double-blind, randomized, placebo controlled study
4) postmarketing surveillance
5) sequential trial
Answers-1
More Questions & Answers:-
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The relative risk of those given the cholesterol lowering medication was 0.8.
What number of patients will need to be treated with active drug for five years to prevent one myocardial infarction?
1) 20
2) 40
3) 50
4) 80
5) 100
Answers-3
2- Regarding standard error of the mean (SEM) and standard deviation (SD) the following ONE statement is true
1) Standard error of mean is calculated by taking the square root of the standard deviation of the sample means
2) Standard deviation invariably falls with increasing sample size
3) Standard error of mean increases with sample size
4) if standard deviation is greater than the mean the distribution is negatively skewed
5) Student's t test is a non-parametric test
Answers-4
3- A publication describes a new diagnostic test for myocardial infarction. You want to know what proportion of patients with a confirmed myocardial infarction will be identified by the test.
Which one of the following measurements would indicate this?
1) Accuracy
2) Negative predictive value
3) Positive predictive value
4) Sensitivity
5) Specificity
Answers-4
4- In a trial of a new drug the following results were obtained:
improved not improved
treatment group 44 16
placebo group 36 26
Which of the following statements regarding the statistical analysis or interpretation of the trial is true?
1) A Student t-test could be used.
2) Pearson's coefficient of linear regression would be an appropriate significance test.
3) The data could be evaluated using the Chi-squared test.
4) The numbers are too small to draw any conclusions.
5) The results so obviously show the benefit of treatment that statistical analysis is not required.
Answers-3
5- A new antihypertensive drug needs to be investigated to establish its relative potency.
Which of the following techniques is most appropriate for this purpose?
1) bioassay
2) case-control study
3) double-blind, randomized, placebo controlled study
4) postmarketing surveillance
5) sequential trial
Answers-1
More Questions & Answers:-
Page1 Page2 Page3 Page4 Page5
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